Abstract #0063

Non-Contrast T1ρ Mapping can Differentiate Hypertrophic Cardiomyopathy from Hypertensive Heart Disease: A Prospective Clinical CMR Study

Danjun Yang¹, Kai Li¹, Haodong Qin², and Jie Zheng³

¹Department of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning ,China, Nanning, Chile, ²MR Research Collaboration, Siemens Healthineers, Guangzhou, China, Guangzhou, China, ³Department of Radiology, Washington University in St. Louis, St. Louis, USA, St. Louis, MO, United States

Synopsis

Keywords: Myocardium, Cardiomyopathy

Motivation: Differentiating hypertrophic cardiomyopathy (HCM) from hypertensive heart disease (HHD) is challenging due to similar clinical and imaging features.

Goal(s): This study aims to explore the effectiveness of T1ρ mapping as a non-contrast imaging method for distinguishing between HCM and HHD.

Approach: We employed non-contrast T1ρ and native T1 mapping on Cardiac magnetic resonance (CMR) in HCM and HHD patients and compared fibrosis metrics.

Results: T1ρ mapping outperformed native T1 in differentiating HCM from HHD, demonstrating superior diagnostic accuracy for fibrosis evaluation.

Impact:

This research employs non-contrast T1ρ mapping to evaluate fibrosis differences between HCM and HHD, providing valuable insights for distinguishing left ventricular hypertrophy, consequently supporting customized, patient-specific treatment approaches.

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