Keywords: Tumors (Post-Treatment), Neuro
Motivation: Accurate preoperative prediction of glioma post-surgery recurrence holds pivotal clinical importance for guiding clinical therapy.
Goal(s): Explore the presurgical tumor and habitat MRI-based radiomics features to identify key biomarkers for the surgical recurrence of glioma.
Approach: 103 glioma patients who underwent preoperative T1-CE and T2WI MRI were prospectively included. Three habitats were identified and radiomics features were extracted, prediction models for recurrence were constructed, model performance was evaluated.
Results: The habitat 2 with a higher volume ratio in recurrence gliomas exhibits a stronger relation to post-surgical recurrence. The combined model of three habitats shows more excellent predictive performance than the whole tumor model.
Impact: The presurgical habitat-based radiomics model may facilitate clinicians in deciding whether to undergo the surgical resection of glioma, thus giving a patient-tailored decision.
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