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Abstract #0101

Impact of Deep Learning denoising and ultra-high density coil array on prostate diffusion imaging

Sherry Shuying Huang1, Xinzeng Wang2, Milica Medved3, Clyve Konrad Follante4, Yun-Jeong Stickle4, Patricia Lan5, Ambereen Yousuf3, Roger Engelmann3, Fraser Robb4, Arnaud Guidon6, Grace Lee3, and Aytekin Oto3
1GE HealthCare, Royal Oak, MI, United States, 2GE HealthCare, Houston, TX, United States, 3Department of Radiology, University of Chicago, Chicago, IL, United States, 4GE HealthCare, Aurora, OH, United States, 5GE HealthCare, Menlo Park, CA, United States, 6GE HealthCare, Boston, MA, United States

Synopsis

Keywords: Prostate, Diffusion Denoising, AI/ML Image Reconstruction, Prostate

Motivation: Multiparametric-MRI (mpMRI) of the prostate is integral in the detection, staging, treatment planning, and targeting for prostate cancer. Particularly diffusion weight imaging (DWI) provides a strong correlation with cancer grade. However, DWI, particularly at high b-value suffers from low SNR.

Goal(s): To improve image quality of DWI, particularly at high-b-value, for prostate MRI-guided clinical care.

Approach: This study employs a novel body-conforming high-density 50-Channel pelvic coil with additional perineal coverage and Deep Learning (DL) based reconstruction for denoising diffusion images.

Results: High density pelvic coil and DL-based reconstruction improves the image quality demonstrated in reader score and statistical measurements.

Impact: This study shows a clinically feasible approach by combining a novel 50-channel pelvic coil with perineal coverage with DL based reconstruction for an improved DWI imaging in prostate MR.

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Keywords