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Abstract #0157

Quantitative MRI Assessment of Paraspinal Muscles using T2 mapping and IDEAL‑IQ in Chronic Non-Specific Low Back Pain in Young Adults

Muqing Luo1, Kun Zhang1, and Weiyin Vivian Liu2
1The First Hospital of Hunan University of Chinese Medicine, ChangSha, China, 2MR Research China, GE Healthcare, Beijing, China

Synopsis

Keywords: Muscle, Quantitative Imaging

Motivation: Diagnosis of chronic non-specific low back pain (CNLBP) has largely relied on subjective symptom assessment, lacking comprehensive pathological insights.

Goal(s): To evaluate the effectiveness of T2 values and fat fraction (FF) measurements in identifying muscle pathology.

Approach: 107 participants prospectively underwent T2 mapping and IDEAL-IQ to measure T2 values and FF in the multifidus and erector spinae.

Results: The results showed significant differences in T2 values and FF at the L4 and L5 levels, achieving high diagnostic accuracy (AUC=91.81%) in detecting CNLBP. This approach offers a promising non-invasive tool for early diagnosis and targeted preventive treatment of unilateral symptoms in CNLBP patients.

Impact: This study highlights the potential of T2 mapping and fat fraction (FF) for detecting early pathological changes in paraspinal muscles of young adults with CNLBP, offering a non-invasive tool to improve early diagnosis and therapy.

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