Keywords: Muscle, Quantitative Imaging
Motivation: Diagnosis of chronic non-specific low back pain (CNLBP) has largely relied on subjective symptom assessment, lacking comprehensive pathological insights.
Goal(s): To evaluate the effectiveness of T2 values and fat fraction (FF) measurements in identifying muscle pathology.
Approach: 107 participants prospectively underwent T2 mapping and IDEAL-IQ to measure T2 values and FF in the multifidus and erector spinae.
Results: The results showed significant differences in T2 values and FF at the L4 and L5 levels, achieving high diagnostic accuracy (AUC=91.81%) in detecting CNLBP. This approach offers a promising non-invasive tool for early diagnosis and targeted preventive treatment of unilateral symptoms in CNLBP patients.
Impact: This study highlights the potential of T2 mapping and fat fraction (FF) for detecting early pathological changes in paraspinal muscles of young adults with CNLBP, offering a non-invasive tool to improve early diagnosis and therapy.
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