Meeting Banner
Abstract #0205

Multiecho Cardiac-Gated fMRI Enhances Activation Detection in Simultaneous Brain-Spinal Cord Imaging

Christine Sze Wan Law1, Merve Kaptan1, Dario Pfyffer1, Yiyu Wang1, Ken Arnold Weber II1, Sean Mackey1, and Gary Glover1
1Stanford University, Stanford, CA, United States

Synopsis

Keywords: fMRI Acquisition, fMRI Acquisition, cardiac-gating, mutliecho, Tedana, fMRI, spinal cord

Motivation: Spinal cord fMRI is crucial for understanding brain-spinal cord connectivity in pain and motor processing but suffers from low signal-to-noise ratio and motion artifacts. Improved methods are needed to accurately detect spinal cord activation.

Goal(s): This study investigates whether multiecho cardiac-gated fMRI improves activation detection compared to single-echo in simultaneous brain-spinal cord imaging.

Approach: Using multiecho and single-echo cardiac-gated fMRI on healthy volunteers, we compared BOLD activation sensitivity in brain and spinal cord regions.

Results: Multiecho cardiac-gating showed superior activation detection across regions, with higher sensitivity and effective reduction of physiological noise in the spinal cord.

Impact: This study demonstrates that multiecho cardiac-gated fMRI enhances spinal cord activation detection, enabling more precise brain-spinal cord connectivity mapping. This advancement could refine clinical assessments of pain and motor disorders, driving further exploration of physiological noise reduction techniques in neuroimaging.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords