Keywords: High-Field MRI, High-Field MRI
Motivation: There is an increasing interest in pursuing ultrahigh resolution human cerebellum MRI at ultrahigh field capitalizing on the increased SNR and CNR.
Goal(s): To demonstrate the feasibility and utility of mesoscale T2*-weighted cerebellum MRI at 10.5T by synergizing various techniques.
Approach: Data were collected at 0.4-mm isotropic resolution with tailored RF shimming, a custom high density head RF array, and fast motion-robust multi-echo 3D EPI. SWI, quantitative R2* and local field maps were obtained.
Results: Our approach produced high quality images, delineating fine cerebellar architecture with improved SNR and contrast.
Impact: The demonstrated feasibility and utility of motion-robust mesoscale multi- echo EPI in humans at 10.5T may shed light on future optimal implementation of anatomical T2*-weighted cerebellum MRI at ultrahigh field, paving the way for future neuroscience applications.
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