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Abstract #0324

Free-Running Time-Resolved 3D+time Cardiovascular MRI at 40 Hz in a One Minute Scan using Cartesian Sampling and CMR-MOTUS

Thomas E. Olausson1,2, Maarten L. Terpstra1,2, Edwin Versteeg1,2, Casper Beijst2, Syed Murtaza Arshad3, Birgitta K. Velthuis4, Cornelis van den Berg1,2, and Alessandro Sbrizzi1,2
1Computational Imaging Group for MR Therapy and Diagnostics, Center for Image Science, University Medical Center Utrecht, Utrecht, Netherlands, 2UMC Utrecht Cancer Center, Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands, 3Biomedical Engineering, The Ohio State University, Columbus, OH, United States, 4Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands

Synopsis

Keywords: Image Reconstruction, Image Reconstruction, Motion Correction; Sparse & Low-Rank Models; Time-Resolved 3D+time Volumetric Imaging; Cardiovascular

Motivation: Free-running Time-Resolved 3D+time cardiovascular MRI is a challenging protocol due to heart and respiratory dynamics.

Goal(s): We propose to extract the time-resolved motion in the acquisition using cartesian sampling at a very high temporal resolution (40Hz) and reduced scan time (about one minute).

Approach: We used the CMR-MOTUS framework to reconstruct motion fields in a deformable mechanical phantom, healthy volunteer, and patient dataset.

Results: Realistic motion fields were reconstructed at 40Hz. In the phantom study, the ejection fraction was correlated with reference values, and high DICE-scores were achieved. This framework could improve patient comfort and enhance clinical workflow by enabling shorter scan time.

Impact: By extracting high-quality time-resolved 3D motion fields at a very high temporal resolution (40Hz), the entire acquisition can be leveraged in the image reconstruction, hence shorter scans. Additionally, time-resolved cardiovascular volumetric analysis is enabled i.e. time-propagating segmentations using motion fields.

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Keywords