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Abstract #0344

Efficient multi-echo steady-state imaging with spatial-resolution enhancement

Coraline Beitone1, Mark Chiew2, Karla L Miller3, Neal K Bangerter1,4, and Peter J Lally1,5
1Bioengineering, Imperial College London, London, United Kingdom, 2Medical Biophysics, University of Toronto, Toronto, ON, Canada, 3Wellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford, United Kingdom, 4Electrical and Computer Engineering, Boise State University, Boise, ID, United States, 5Centre for Care Research and Technology, UK Dementia Research Institute, London, United Kingdom

Synopsis

Keywords: New Trajectories & Spatial Encoding Methods, Acquisition Methods, SSFP, bSSFP, multi-contrast imaging, super-resolution

Motivation: Multi-echo steady-state techniques enable efficient relaxometry by rapidly acquiring multiple imaging contrasts, but require strong gradients or low through-plane resolution to minimize artifact

Goal(s): Propose an efficient multi-contrast acquisition/reconstruction strategy providing isotropic spatial resolution for both morphological and quantitative tissue analysis.

Approach: Exploiting RF phase and gradient spoiling effects on steady-state signal dynamics, higher-frequency information can be included within the nominally sampled k-space region, and retrospectively extracted through a physics-informed process to produce super-resolution images.

Results: Applied to in vivo 3D brain and knee experiments at 3T, our approach yields simultaneously 3 contrast images with enhanced spatial resolution and preserved contrast features.

Impact: Our proposed strategy shows promise as an efficient trade-off between high spatial-resolution, artifact minimisation, and SNR requirements, enabling efficient relaxometry and morphological imaging in a single rapid protocol.

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Keywords