Abstract #0353

Toward a 6-minute quantitative multi-dimensional assessment of cardiovascular system (qMACS)

Qingle Kong¹, Yang Chen¹, Junzhou Chen¹, Jiayu Xiao¹, Sophia X. Cui², Anthony G. Christodoulou³, Debiao Li⁴, John C. Wood^1,5, and Zhaoyang Fan^1,5

¹Department of Radiology, University of Southern California, Los Angeles, CA, United States, ²Siemens Medical Solutions USA, Los Angeles, CA, United States, ³Department of Radiological Sciences, University of California, Los Angeles, CA, United States, ⁴Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ⁵Department of Pediatrics, University of Southern California, Los Angeles, CA, United States

Synopsis

Keywords: Myocardium, Cardiovascular, T1/T2 mapping, free‐breathing, ECG-free, multi-contrast

Motivation: MR holds great potential for comprehensive cardiovascular imaging. However, conventional protocols are prohibitively long and highly demanding for expertise and patient cooperation.

Goal(s): To develop a quantitative multi-dimensional assessment of cardiovascular system (qMACS) technique that provides multi-contrast qualitative and quantitative cardioaortic imaging through a 6-min scan.

Approach: qMACS builds on a continuous magnetization-prepared hybrid-radial FLASH acquisition and an optimized image reconstruction pipeline based on MR Multitasking. Phantom and human studies were performed at 3T.

Results: qMACS provided good to excellent qualitative and quantitative imaging based on assessment of image quality scores, inter-reader agreement, and comparison with reference mapping methods.

Impact: qMACS is a time-efficient and patient-friendly technique for simultaneous quantitative and qualitative imaging of the whole cardioaortic system and may be used as a gatekeeper approach to the diagnosis of a variety of cardiovascular diseases.

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