Abstract #0355

Wideband myocardial T2 mapping in patients with implantable cardiac devices at 1.5T

Pauline Gut^1,2,3, Daniel Kim^4,5, Hubert Cochet^2,6, Frederic Sacher^2,7, Pierre Jaïs^2,7, Matthias Stuber^1,2,8, and Aurélien Bustin^1,2,6

¹Diagnostic and Interventional Radiology, University Hospital of Lausanne, Lausanne, Switzerland, ²Heart Rhythm Disease, IHU LIRYC, Pessac, France, ³Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland, ⁴Biomedical Engineering, Northwestern University, Chicago, IL, United States, ⁵Radiology, Northwestern University, Chicago, IL, United States, ⁶Cardiovascular Imaging, Hôpital Cardiologique du Haut-Lévêque, Pessac, France, ⁷Cardiac Pacing and Electrophysiology, Hôpital Cardiologique du Haut-Lévêque, Pessac, France, ⁸CIBM Center for Biomedical Imaging, Lausanne, Switzerland

Synopsis

Keywords: Inflammation, Infiltration, Tissue Characterization, Implantable cardiac devices, T2 mapping, artifact reduction

Motivation: Myocardial T2 mapping in the presence of implantable cardiac devices is typically not performed due to severe image artifacts that result in inaccurate T2 values.

Goal(s): To enable myocardial T2 mapping in the presence of implantable cardiac devices by reducing device-related artifacts and providing accurate T2 values.

Approach: A 2D breath-held, ECG-triggered, single-shot wideband GRE T2 mapping sequence, integrating a wideband T2preparation, was developed on a 1.5T system and tested in phantoms, volunteers, and patients.

Results: The proposed sequence effectively reduced device-related artifacts and provided accurate myocardial T2 values in both phantom and in-vivo studies, addressing the limitations of conventional GRE T2 mapping.

Impact: The proposed wideband T2 mapping sequence represents a significant advancement in myocardial T2 mapping for patients with implantable cardiac devices, offering a reliable method for assessing myocardial inflammation and edema, where conventional methods fail.

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