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Abstract #0362

Inline Implementation of a Multi-Breathhold 3D Cine Framework: A Feasibility Study

Karl Philipp Kunze1,2,3, Isaac Watson1, Oscar J Goldman2,3, Amedeo Chiribiri2,3, and Radhouene Neji2,3
1MR Research Collaborations, Siemens Healthcare Limited, Camberley, United Kingdom, 2Imaging Physics and Engineering Research Department, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom, 3Cardiovascular Imaging Research Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

Synopsis

Keywords: Myocardium, Cardiovascular

Motivation: Current 2D cine CMR is acquired slice-by-slice in prospectively planned views, leading to many breathholds and highly skilled operator input at scan time.

Goal(s): Developing isotropic 3D cine CMR for reduced scan complexity and time, with images being retrospectively reformattable into desired slice positions.

Approach: A multi-breathhold framework with 2-region k-space sampling that is varied across cardiac phases and breathholds, and reconstruction with temporal regularization and integrated motion-compensation.

Results: Excellent ability of the proposed framework to depict diastolic/systolic phases and handle inter-breathhold motion was seen in 4 healthy subjects and 2 patients.

Impact: We propose a 3D cine CMR framework acquiring data efficiently over 2-3 of breathholds and a reconstruction that can handle potential inter-breathhold motion. Images can be retrospectively reformatted into desired slice positions minimising operator input at scan time.

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