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Abstract #0386

Noise Analysis in Physics-based Deep Unrolled Network Reconstructions

Onat Dalmaz1,2, Arjun Desai1, Akshay Chaudhari2,3, and Brian A Hargreaves1,2,4
1Electrical Engineering, Stanford University, Stanford, CA, United States, 2Radiology, Stanford University, Stanford, CA, United States, 3Biomedical Data Science, Stanford University, Stanford, CA, United States, 4Bioengineering, Stanford University, Stanford, CA, United States

Synopsis

Keywords: AI/ML Image Reconstruction, AI/ML Image Reconstruction

Motivation: Characterizing noise is crucial for MRI reconstruction to ensure accurate SNR and image quality. However, current deep learning-based methods often neglect noise propagation.

Goal(s): Develop a tool to analyze noise propagation of physics-based deep unrolled network reconstructions without relying on computationally intensive Monte Carlo simulations.

Approach: Express image covariance via neural network's Jacobian, imaging operator, and coil covariance. Introduce a memory-efficient iterative algorithm that computes variance maps, avoiding full Jacobian storage.

Results: Our technique accurately computes noise variance maps for state-of-the-art unrolled MRI reconstruction techniques, closely matching Monte-Carlo simulation results. Extremely low SNR levels and high acceleration factors reduce variance estimation accuracy.

Impact: A practical tool facilitates noise analysis in physics-based deep learning reconstructions, so that image SNR can be assessed more objectively between reconstructions and patient scans. This would encourage researchers to develop more robust and trustworthy algorithms.

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