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Abstract #0517

Diffusion MRI with a Multi-Shot Rosette Readout

Kevin D Harkins1, Jonathan B Martin1, and Mark D Does2
1Vanderbilt University Medical Center, Nasvhille, TN, United States, 2Vanderbilt University, Nasvhille, TN, United States

Synopsis

Keywords: Diffusion Acquisition, Diffusion Acquisition

Motivation: Demonstrate image quality of multi-shot rosette acquisitions in diffusion-weighted MRI (dMRI) in both ex vivo and in vivo applications.

Goal(s): Use redundant k-space sampling of rosette readouts to measure and correct for magnetic fields (B0 and shot-to-shot phase variations) that typically cause distortions in dMRI acquisitions

Approach: Rosette dMRI acquisitions were evaluated on ex vivo ferret brains and in vivo mouse spinal cords.

Results: Incorporating B0 and shot-to-shot phase variations estimated from rosette acquisitions without the need prescans showcases the potential of rosette readouts in advancing dMRI image quality.

Impact: This abstract demonstrates multi-shot rosette readouts in diffusion MRI, including using redundant k-space information for estimating B0 and phase variations to improve image quality, evaluated in ex vivo ferret brains and in vivo mouse spinal cord.

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Keywords