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Abstract #0534

Self-contained Small Animal Imaging Insert for Clinical MRI Systems

Tobias Lobmeyer1, Alireza Abaei2, Fabian Bschorr1, Thomas Huefken1, and Volker Rasche1
1University Hospital Ulm, Ulm, Germany, 2Core Facility Small Animal Imaging (CF-SANI), University of Ulm, Ulm, Germany

Synopsis

Keywords: Small Animals, Small animals

Motivation: To enable small animal imaging studies at clinical field strength and systems, for improving transferability and duty cycle of human scanners.

Goal(s): Introducing an easy-to-use system that allows for positioning, monitoring, heating and local SNR enhancement, enabling small animals scans.

Approach: Using inductively coupled resonant structures, a wire free local sensitivity enhancement of the hosts built-in coils is achieved. A fixation and holder system with adapters to connect ECG and breathing bellows to the host were designed.

Results: Local SNR enhancement of up to 32 in comparison to the inbuilt coils is reached. ECG and respiratory gating allowed for triggered in-vivo scans.

Impact: The easy-to-use system shows adequate SNR for imaging mice in-vivo. The possibility of using the clinical scanners console, sequences, the main magnetic field and the gradient system, allows for a high degree of transferability between preclinical and clinical trials.

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