Abstract #0542

Motion Robust Gradient Echo-based T2 Mapping Using Readout Alternation for Pediatric Liver Imaging

Daiki Tamada¹, Lukas Müller¹, Diego Hernando^1,2, and Scott B Reeder^1,2,3,4,5

¹Radiology, University of Wisconsin-Madison, Madison, WI, United States, ²Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ³Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ⁴Medicine, University of Wisconsin-Madison, Madison, WI, United States, ⁵Emergency Medicine, University of Wisconsin-Madison, Madison, WI, United States

Synopsis

Keywords: Motion Correction, Acquisition Methods, Motion-insensitive imaging

Motivation: Motion artifacts in liver T2 mapping hinder accurate diagnosis in pediatric patients. Existing GRE-based T2 mapping methods are sensitive to motion, reducing their clinical utility for whole-liver imaging.

Goal(s): To evaluate whether readout alternation (ROA) improves the motion robustness of GRE-based T2 mapping for pediatric liver imaging.

Approach: Motion phantom and pediatric volunteer studies were conducted using GRE-based T2 mapping with and without ROA. T2 map quantitative accuracy was assessed under motion conditions.

Results: ROA reduced motion artifacts, improving T2 map homogeneity and measurement consistency in both phantom and volunteer studies, demonstrating enhanced motion robustness in GRE-based T2 mapping.

Impact: Implementing readout alternation (ROA) in GRE-based T2 mapping enhances motion robustness, enabling reliable whole-liver imaging. This advancement may improve diagnostic capabilities for liver diseases and encourage broader clinical adoption of rapid T2 mapping techniques in populations prone to motion artifacts.

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