Keywords: Cartilage, MSK, Data Harmonization
Motivation: Longitudinal T1ρ and T2 measurements can help to understanding hip cartilage degeneration. However, inter-scanner variability introduces biases, complicating data interpretation.
Goal(s): Harmonize scanner-related batch effects in longitudinal hip cartilage T1ρ and T2 data over an eight-year follow-up.
Approach: The longitudinal ComBat method was used to mitigate scanner-induced biases and ensure data consistency.
Results: ComBat harmonization effectively reduced scanner biases. Analysis showed an increase in T1ρ and T2, particularly in females aged 50 and above.
Impact: The harmonized longitudinal T1ρ and T2 data provides insights into hip cartilage degeneration, aiding in understanding osteoarthritis progression.
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