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Abstract #0622

Segment-Any-Muscle: Towards an Open-Source, Contrast-Agnostic Computer-Vision Muscle Segmentation Model for MRI and CT

Eddo Wesselink1, James Elliott2, Marnee McKay2, Enrico de Martino3, Nick Caplan4, Sean Mackey1, Julien Cohen-Adad5, Sandrine Bédard5, Benjamin de Leener5, Enamundram Naga Karthik5, Christine Law1, Maryse Fortin6, Carmen Vleggeert – Lankamp 7, Antonio di Ieva8, Brian Kim2, Mark Hancock8, Annelies Pool - Goudzwaard9, Philip Pevenage10, and Kenneth Arnold Weber II1
1Stanford University, Palo Alto, CA, United States, 2Sydney University, Sydney, Australia, 3Aalborg University, Aalborg, Denmark, 4Northrumbia, Newcastle, United Kingdom, 5Polytechnique Montreal, Montreal, QC, Canada, 6Concordia University, Montreal, QC, Canada, 7LUMC Medical Center, Leiden, Netherlands, 8Macquarie University, Sydney, Australia, 9SOMT University, Amersfoort, Netherlands, 10MRI centrum, Amsterdam, Netherlands

Synopsis

Keywords: Analysis/Processing, Segmentation

Motivation: Declines in muscle health are common in multiple conditions, and MRI is the gold standard for non-invasively assessing muscle. Computer-vision models show promise for the automated quantification of muscle health with MRI but lack generalizability across sequences and imaging modalities.

Goal(s): To develop a contrast-agnostic computer-vision muscle segmentation model for the lumbar paraspinal muscles that generalizes to multiple MRI contrasts as well as CT.

Approach: We trained, tested, and validated the model on over 1,500 MRI and CT images.

Results: The model showed high accuracy (Sørensen-Dice≥0.865) on an external, multimodal validation dataset and can be accessed at github.com/MuscleMap/MuscleMap.

Impact: This contrast-agnostic computer-vision model can automatically and accurately assess muscle health from both MRI and CT. We are expanding this to all muscles to support multiple clinical and research applications linking muscle health to overall health and disease.

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Keywords