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Abstract #0666

An Ensemble Framework for Automatic Quantification of Image Distortion in Prostate Diffusion-Weighted Imaging

Haoran Sun1,2, Lixia Wang1, Hsu-Lei Lee1, Vibhas S. Deshpande3, Fei Han3, Chang Gao3, Robert Grimm4, Debiao Li1, and Yibin Xie1
1Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 2Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States, 3Siemens Healthineers, Austin, TX, United States, 4Siemens Healthineers, Forchheim, Germany

Synopsis

Keywords: Prostate, Diffusion Analysis and Visualization, Prostate, Machine Learning/Artificial Intelligence

Motivation: Diffusion-weighted imaging(DWI) is essential for prostate cancer imaging; however, its susceptibility to image distortion presents challenges in radiology interpretation. Automatic quantification of the level of image distortion could provide immediate feedback to scan operators, potentially reducing patient recalls.

Goal(s): This study aimed to develop an ensemble machine-learning framework for the automatic assessment of distortion in prostate DWI.

Approach: The framework integrates distortion factors derived from both segmentation-based and registration-based computational methods, employing ensemble learning to improve classification accuracy.

Results: The proposed ensemble model demonstrated superior performance in accurately classifying distortion ranks, achieving AUCs of 1.0, 0.93, 0.93 in distinguishing the three distortion levels.

Impact: The developed ensemble framework for automatic assessment of image distortion may assist in acquiring high-quality prostate DWI and reducing patient recalls.

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Keywords