Abstract #0670

Self-Improved Multi-Shot Abdominal Diffusion-Weighted Imaging: A Motion-Resolved High-Resolution Solution

Hui Zhang¹, Fanwen Wang², Nannan Shi³, Peng Wu⁴, Zhang Shi⁵, Yikun Wang⁶, Xiuzheng Yue⁷, Weibo Chen⁴, Rencheng Zheng¹, Chengyan Wang⁸, and He Wang¹

¹Institute of Science and Technology for Brain- Inspired Intelligence, Fudan University, Shanghai, China, ²Department of Bioengineering and Imperial-X, Imperial College London, London, United Kingdom, ³Department of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China, ⁴Philips Healthcare, Shanghai, Shanghai, China, ⁵Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China, ⁶Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, ⁷Philips Healthcare, Beijing, Beijing, China, ⁸the Human Phe- nome Institute, Fudan University, Shanghai, China

Synopsis

Keywords: Liver, Diffusion Reconstruction, high-resolution DWI, abdominal，liver

Motivation: Successful neural high-resolution DWI methods are limited for abdominal imaging due to severe respiratory motion, cardiac pulsations, and intestinal peristalsis, which cause ghosting, misregistration, blurring, and signal attenuation.

Goal(s): We propose a motion-resolved, self-adaptive solution for high-resolution abdominal DWI.

Approach: The novel motion correction solution for multi-shot high-resolution abdominal DWI, called MoCo-mDWI, combines an adaptive motion-resolved acquisition with self-improvement preparation and DL-based motion deblurring.

Results: Preliminary results showed that MoCo-mDWI significantly outperformed traditional multi-shot and single-shot DWI techniques in ghost-to-signal ratio (GSR) and overall image quality.

Impact: The proposed solution enables in-vivo high-resolution abdominal DWI in clinical practice.

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