Keywords: DWI/DTI/DKI, Acquisition Methods, Hepatocellular carcinoma, Simultaneous multislice imaging, Early recurrence, Prognosis.
Motivation: While DKI effectively predicts HCC malignancy, its clinical use is limited by lengthy acquisition times (4–5 min). Simultaneous Multi-Slice (SMS) technology shortens DKI scan times in liver imaging, yet its potential for predicting HCC recurrence remains unexplored.
Goal(s): To evaluate SMS-DKI for predicting early recurrence in HCC and develop a predictive model.
Approach: Sixty-seven HCC patients underwent MRI with SMS-accelerated DKI (140 sec) and routine sequences. Diffusion parameters and radiological features were analyzed by three radiologists.
Results: SMS-MK, non-smooth margins, absence of capsule, and larger tumor volume were independent predictors, achieving an AUC of 0.94 in predictive model.
Impact: The improved acquisition speed using SMS may facilitate the integration of DKI into routine liver imaging workflows. This preliminary evidence for SMS-DKI in predicting early recurrence in HCC also encourages further exploration of its applicability in other tumor types.
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