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Abstract #0788

Assessing the Value of Stress Cardiac Magnetic Resonance Imaging in Detection of Myocardial Ischemia

Lu Zhou1, Jing An2, Mengzhu Wang3, and Yinghui Ge4
1Department of Radiology, Fuwai Central China Cardiovascular Hospital, ZhengZhou, China, 2DL,Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, 3MR Research Collaboration, Siemens Healthineers Ltd, Beijing, China, 4Fuwai Central China Cardiovascular Hospital, ZhengZhou, China

Synopsis

Keywords: Myocardium, Cardiovascular

Motivation: Coronary microvascular dysfunction (CMD) can cause myocardial ischemia without significant coronary artery disease, hindering its diagnosis.

Goal(s): To evaluate the diagnostic performance of non-invasive stress cardiac magnetic resonance (CMR) perfusion parameters, particularly myocardial perfusion reserve (MPR), in detecting and distinguishing CMD from obstructive coronary artery disease (CAD).

Approach: We prospectively analyzed stress CMR perfusion data from patients with suspected myocardial ischemia. Patients underwent coronary angiography and/or coronary computed tomography angiography for comparison.

Results: Stress CMR detected ischemia in more patients and myocardial segments relative to resting perfusion imaging. MPR showed high diagnostic accuracy for CMD.

Impact: This study demonstrates the utility of stress CMR for identifying CMD, even in patients with non-obstructive CAD, thus enabling earlier diagnosis and potential intervention. Further research is needed concerning the long-term prognostic and therapeutic utilities of stress CMR for CMD.

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