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Abstract #0795

Repeatability of an MR elastography biomarker for quantitatively assessing myofascial interface mobility in chronic lower back pain

Emi Hojo1, Yi Sui1, Xiang Shan1, Keni Zheng1, Phillip Rossman1, Tim Waters1, Armando Manduca2, Garret M. Powell1, Kai-Nan An3, Kristin D. Zhao4, Brent A. Bauer5, Richard L. Ehman1, and Ziying Yin1
1Radiology, Mayo Clinic College of Medicine, Rochester, MN, United States, 2Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, Rochester, MN, United States, 3Orthopedics Research, Mayo Clinic College of Medicine, Rochester, MN, United States, 4Physical Medicine and Rehabilitation, Mayo Clinic College of Medicine, Rochester, MN, United States, 5General Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN, United States

Synopsis

Keywords: Elastography, Elastography, muscle, slip interface imaging, myofascial tissue, myofascial mobility, muscle function, repeatability

Motivation: Myofascial interface adhesion involving paraspinal muscles is considered a key factor in chronic low back pain associated with myofascial pain syndrome, providing motivation for developing an imaging-based technique for quantitatively assessing myofascial mobility in the lower back.

Goal(s): To validate the repeatability of MR Elastography-based slip interface imaging (SII) for quantifying myofascial mobility in the lower back of healthy participants.

Approach: To assess within-day and between-day repeatability of a new SII biomarker for lumbar inter-muscular myofascial interfaces.

Results: SII shows high repeatability, with moderate-to-excellent Intraclass-Correlation-Coefficient and excellent within-subject coefficient of variation, demonstrating its potential for quantifying myofascial interface mobility.

Impact: The study demonstrated a non-invasive imaging technique for quantifying myofascial mobility in the lower back, with promising repeatability metrics suggesting SII could serve as a reliable biomarker for assessing myofascial adhesion in MPS patients with chronic low back pain.

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Keywords