Meeting Banner
Abstract #0798

Implementing Magnetic Resonance Elastography in the MAGNUS for Evaluation of High-Performance Gradient Coil Effects

Herman Douglas Morris1, Emily R Long2, Cate Wisdom3, George Klarmann3, Dzung Pham4, and Vincent B Ho4
1Radiology and Bioengineering, Uniformed Services University, Bethesda, MD, United States, 2Radiology, Uniformed Services University / Johns Hopkins University, Bethesda, MD, United States, 3Geneva Foundation / USUHS, Bethesda, MD, United States, 4Radiology, Uniformed Services University, Bethesda, MD, United States

Synopsis

Keywords: Elastography, Elastography

Motivation: Enhanced gradient systems have the potential to significantly improve brain MRE, but their impact on data quality and acquisition parameters remains unclear.

Goal(s): Our objective was to evaluate the influence of high-amplitude gradients on motion encoding efficiency and overall data quality in brain MRE.

Approach: We conducted a human observational study and validated our findings using an anthropomorphic brain phantom.

Results: High-amplitude gradients substantially improved motion encoding efficiency, leading to enhanced OSS-SNR up to a threshold of about 3 µm/rad. However, exceeding this efficiency threshold resulted in a rapid decline in OSS-SNR due to phase wrap.

Impact: This study clarifies the advantages and limitations of high-performance gradient systems for brain MRE, guiding protocol optimization, inversion and signal processing methods, and acquisition techniques while furthering our understanding of applications best suited for high-performance gradients.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords