Keywords: Pulse Sequence Design, Myocardium, Low-Field MRI
Motivation: 3D whole-heart joint T1/T1ρ/T2 mapping has recently been proposed at 0.55T with continuous wave (CW) T1ρ-preparation. However, the CW T1ρ spin-lock amplitude was relatively small limiting T1ρ dispersion.
Goal(s): To develop a novel free-breathing, 3D joint T1/T1ρ-adiabatic/T2 mapping sequence, with adiabatic T1ρ-preparation to improve dispersion, to provide whole-heart T1, T1ρ-adiabatic, and T2 maps and co-registered water/fat volumes in a ~10 min scan at 0.55T.
Approach: The sequence was tested on phantoms and in-vivo with 4 healthy subjects and 1 patient and compared with conventional 2D mapping references.
Results: Preliminary 3D joint T1/T1ρ-adiabatic/T2 mapping results demonstrate good agreement in phantoms and promising results in-vivo.
Impact: 3D whole-heart T1, T1ρ-adiabatic and T2 maps and co-registered water-fat volumes with isotropic resolution for comprehensive myocardial tissue characterization can be obtained in a single scan of ~10 min at 0.55T.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords