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Abstract #0829

Tissue-susceptibility matched electrodes for simultaneous magnetic resonance imaging

Aaron von Raven1
1Max Planck Institute for biological cybernetics, Tuebingen, Germany

Synopsis

Keywords: Probes & Targets, Electromagnetic Tissue Properties, Electrophysiology

Motivation: How does measured fMRI signal resembles the underlying neural activity?

Goal(s): Here we present a new approach of a setup, which allows simultaneous recording of neural signals during fMRI measurements at a field strength of 14.1 Tesla.

Approach: The electrode design combines different materials, which alone do not have the electrical, mechanical and bio-compatible properties but together they do. Special galvanisation lowered the impedance. The susceptibility artifact was tested with a echo planar imaging. Biocompatibility was tested in in-vitro studies.

Results: In-vivo electrophysiology during echo-planar imaging reached a noise level of less than 12µV at the input of the electrode after post-processing.

Impact: The presented electrode is an alternative to conventional electrodes, especially at ultrahigh field strengths. Since it was possible to perform simultaneous echo-planar imaging and voltage recording, those electrodes could be used for animal experiments to gain improved functional information.

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Keywords