Keywords: Dementia, AI/ML Image Reconstruction
Motivation: MPRAGE is useful for voxel-based morphometry (VBM) but is not a priority in routine clinical examinations. We hypothesized that converting MRI localizer (AutoAlignHead, AAH) to MPRAGE would be beneficial for subjects who did not have MPRAGE.
Goal(s): We aimed to establish and evaluate a Pix2Pix-based model for generating MPRAGE-like images from AAH.
Approach: Training, validation, and test datasets of 340 patients were included. The test set was evaluated with visual examination by radiologists and quality metrics of PSNR, SSIM, and LPIPS. VBM using Freesurfer was also performed.
Results: Visual examination, image metrics, and VBM showed comparable scores between generated and original images.
Impact: MPRAGE-like images generated from MRI localizer images and the reference MPRAGE image showed good agreement with respect to visual assessment of medial temporal lobe atrophy by radiologists. Voxel-based morphological analysis was also acceptable for evaluation of temporal lobe atrophy.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords