Meeting Banner
Abstract #0908

Quantitative Assessment of Pulmonary Function Distribution in the Sitting, Supine, and Prone Postures Using PREFUL MRI with an Open Scanner

Arthur Harrison1,2, Thomas Meersmann1,2,3, Galina E Pavlovskaya1,2, Penny Gowland1,2, Jan A Paul1,2, Rashed Sobhan1,2, and Olivier Mougin1,2
1Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom, 2Nottingham NIHR Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom, 3Centre for Life Science and Health Care, University of Nottingham, Ningbo, China

Synopsis

Keywords: Lung, Lung

Motivation: Regional variations in pulmonary ventilation and perfusion profoundly impacts respiratory function; understanding their distribution and underlying mechanisms is critical for improving therapeutic interventions and patient outcomes.

Goal(s): To investigate the redistribution of regional lung function between different postures in both the apex-to-base and anterior-to-posterior directions.

Approach: Participants were investigated sagittally using an Open 0.5T MRI in three postures: sitting, supine and prone to vary the relative direction of gravity experienced by the lungs.

Results: Results showed significant redistribution of lung function between each of the three postures, both in the apical-to-basal and anterior-to-posterior directions.

Impact: A deeper understanding of lung function variability in response to postural changes will enhance clinical decision-making in pulmonary medicine. Additionally, posture dependent lung function could serve as a marker for lung disease and support stratified treatment approaches.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords