Abstract #0920

Spin-lock based Magnetic Resonance Fingerprinting enables characterization of magnetic waveforms via spectral matching of rotary excitation

Maximilian Gram^1,2, Petra Albertova^1,2, Tom Griesler³, Peter Dawood², Jannik Stebani^2,4, Martin Blaimer⁴, Nicole Seiberlich⁵, Peter Michael Jakob², and Peter Nordbeck¹

¹Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany, ²Experimental Physics 5, University of Würzburg, Würzburg, Germany, ³Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States, ⁴Fraunhofer Institute for Integrated Circuits IIS, Würzburg, Germany, ⁵Department of Radiology, University of Michigan, Ann Arbor, MI, United States

Synopsis

Keywords: Novel Contrast Mechanisms, MR Fingerprinting, spin-lock, rotary excitation

Motivation: Spin-lock based MRI techniques may enable direct non-invasive assessment of bioelectrical currents arising from neuronal or cardiac activity with high spatio-temporal resolution.

Goal(s): This study aims to characterize the temporal evolution of ultra-low magnetic fields using a novel MR-Fingerprinting-like approach combined with the rotary excitation (REX) effect, which occurs during spin-locking.

Approach: By measuring REX responses across different spin-lock frequencies and comparing them to a simulated dictionary, the temporal characteristics of various magnetic stimuli were identified in a phantom setup.

Results: REX responses were matched successfully to waveform shapes with 97% accuracy, demonstrating the potential of this method for detailed magnetic field characterization.

Impact: This study progresses the research and understanding of spin-lock-based magnetic field detection. Magnetic waveforms were characterized by combining concepts from Magnetic Resonance Fingerprinting and the rotary-excitation effect. This method could pave the way for in vivo characterization of biomagnetic fields.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.