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Abstract #0924

Free-running Cardiac MRF for Simultaneous T1, T2 Mapping and Cine Imaging at 0.55 T

Diego Pedraza1,2, Carlos Castillo-Passi1,2,3, Karl P. Kunze4, René M. Botnar1,2,3,5, and Claudia Prieto2,3,5
1Institute for Biological and Biomedical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 2Millennium Institute for Intelligent Healthcare Engineering, Santiago, Chile, 3School of Biomedical Engineering, King's College London, London, United Kingdom, 4MR Research Collaborations, Siemens Healthcare Limited, Camberley, United Kingdom, 5School of Engineering, Department of Electrical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile

Synopsis

Keywords: Quantitative Imaging, MR Fingerprinting

Motivation: Cardiac cine MRF is a powerful quantitative imaging technique that enables comprehensive tissue characterization and left ventricular functional assessment in a single-scan. However, it has not been demonstrated at 0.55T.

Goal(s): To investigate the feasibility of a bSSFP free-running cardiac-MRF sequence at 0.55T for simultaneous T1/T2 and cine-imaging in a single breath-hold-scan of ~13s.

Approach: The sequence, implemented in Pulseq, uses continuous tiny-golden-angle radial bSSFP readouts with IR-T2-prep modules. Phantom results were compared against IR-SE references and in-vivo results against previously reported literature values.

Results: T1/T2-maps show good agreement with phantom reference and in-vivo results show good image quality for T1/T2-maps and cine-images.

Impact: A simultaneous acquisition of T1 and T2 maps, along with cine imaging at 0.55T in a single ~13s scan could provide a more affordable and accessible approach to assess cardiovascular disease.

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