Keywords: Cartilage, Cartilage, MSK, Trauma, T2*, 7T, UHF
Motivation: Medial meniscus posterior root tears (MMPRTs) cause the meniscus to extrude, which increases contact stresses on the cartilage and accelerates the risk of knee osteoarthritis.
Goal(s): Evaluate degenerative changes in the medial femoral cartilage of patients with MMPRT.
Approach: Conduct 3D T2* mapping of cartilage at 7T in patients before and after MMPRT repair and in matched healthy controls.
Results: Compared to the controls, pre-repair patients showed significantly increased T2* values in the posterior, posterior weight-bearing, and central weight-bearing regions of the medial femoral cartilage; while post-repair patients, had significantly elevated T2* values only in the posterior weight-bearing region.
Impact: Post-operative monitoring of articular cartilage with 3D T2* mapping at 7T, which benefits from an enhanced signal-to-noise ratio, provides valuable insights into healing progression, guides timely treatments and potentially helps prevent osteoarthritis.
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