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Abstract #0984

Ultrashort Echo Time Magnetization Transfer Imaging of Lumbar Nerve Roots: A Study of Low Back Pain

Jin Liu1, Yong Lu1, and Yajun Ma2
1Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, 2University of California San Diego, San Diego, CA, United States

Synopsis

Keywords: Neurography, MSK

Motivation: The quantitative magnetization transfer (MT) technique combined with ultrashort echo time (UTE) sequences (UTE-MT) has enabled valuable assessment of macromolecular changes in collagen- or myelin-rich tissues.

Goal(s): The aim of this study is to evaluate the relationship between UTE-MT ratio (UTE-MTR) of lumbar nerve root and low back pain.

Approach: We evaluated compositional changes in compressed nerve roots and their relationship with LBP in 176 LDH patients (L4/5-L5/S1) using UTE-MT and T2 measurement sequences.

Results: Our results indicate that UTE-MT is a promising technique for evaluating the compositional changes of compressed nerve roots in lumbar radiculopathy and their relationship with LBP.

Impact: UTE-MT is a promising technique for evaluating the compositional changes of compressed nerve roots in lumbar radiculopathy and their relationship with LBP.

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