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Abstract #1087

Submucosal Linear Enhancement in Adjusted VI-RADS: Enhancing Detection of Muscle-Invasive Bladder Cancer Using Isotropic DCE-MRI

Xinxin Zhang1, Yichen Wang1, Sicong Wang2, Yan Chen1, and Xinming Zhao1
1National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 2GE Healthcare, MR Research China, Beijing, 100176, China, Beijing, China

Synopsis

Keywords: Cancer, Bladder, cancer

Motivation: The Vesical Imaging Reporting and Data System (VI-RADS) is widely used to evaluate muscle invasion, but it has inherent limitations. Discontinuous submucosal linear enhancement (SLE) may suggest muscle-invasive bladder cancer (MIBC).

Goal(s): The aim was to evaluate the value of incorporating SLE into the VI-RADS to improve muscle invasion prediction in bladder cancer.

Approach: Three-dimensional isotropic DCEI data were reformatted into arbitrary planes across different phases to classify SLE as continuous, disrupted, or absent. An adjusted VI-RADS score was developed by integrating SLE status and VI-RADS.

Results: The adjusted VI-RADS score significantly improved the performance for predicting MIBC compared to the standard VI-RADS.

Impact: Incorporating submucosal linear enhancement (SLE) into the VI-RADS system significantly improves the detection of muscle-invasive bladder cancer. This adjustment could lead to earlier, more accurate staging and treatment planning, ultimately enhancing patient outcomes by reducing missed diagnoses of MIBC.

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