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Abstract #1136

Deep Learning-Optimized GRASP-Pro Reconstruction for Highly-Accelerated DCE-MRI

Haoyang Pei1,2,3 and Li Feng1,2
1Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, 2Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, 3Department of Electrical and Computer Engineering, NYU Tandon School of Engineering, New York, NY, United States

Synopsis

Keywords: Sparse & Low-Rank Models, Image Reconstruction, DCE-MRI

Motivation: Even though GRASP-Pro has been proven to be effective in various applicatioins, it presents a significant challenge at high acceleration/frame rates as the performance of standard GRASP-Pro reconstruction can be significantly compromised under this condition.

Goal(s): This work aim to develop self-supervised learning-optimized GRASP-Pro reconstruction approach to improve 4D dynamic MRI reconstruction at high acceleration rates.

Approach: This approach employs self-supervised learning to first reconstruct high-quality low-resolution images to estimate a accurate temporal basis. Subsequently, self-supervised learning is applied again to reconstruct full-resolution 4D dynamic images using a low-rank subspace-assisted network training.

Results: This approach demostrates improved reconstruction quality for highly-accelerated 4D DCE-MRI.

Impact: The proposed self-supervised learning-optimized GRASP-Pro enables efficient and reliable 4D MRI reconstruction. This improves reconstruction quality for highly-accelerated 4D dynamic MRI, which is useful in various applications such as DCE-MRI.

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Keywords