Abstract #1210

Simultaneous Gadolinium-free MR Angiography, Venography and Relaxometry using a fast 3D MR-STAT protocol

Martin B Schilder¹, Stefano Mandija¹, Hanna Liu¹, Edwin Versteeg¹, Miha Fuderer¹, Oscar van der Heide¹, Mark Haacke², Thierry G Meerbothe¹, Tom J Snijders³, Pierre A J T Robe³, Cornelis A T van den Berg¹, and Alessandro Sbrizzi¹

¹Computational Imaging Group, Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands, ²Departments of Neurology and Radiology, Wayne State University, Detroit, MI, United States, ³Department of Neurology & Neurosurgery, Brain Center, University Medical Center Utrecht, Utrecht, Netherlands, UMC Utrecht, Utrecht, Netherlands

Synopsis

Keywords: Blood Vessels, Quantitative Imaging, MR-STAT, MR Angiography, MR Venography

Motivation: MR-STAT offers fast k-space acquisition, from which T1, T2 and PD maps can be reconstructed, enabling both quantitative analyses and contrast-weighted image synthesis from a single short scan. We assessed the potential to derive gadolinium-free whole-brain MR Angiography and MR Venography from the same short acquisition.

Goal(s): To investigate the potential of MR-STAT to also perform gadolinium-free MRA/MRV at no additional scan time.

Approach: We visually assessed anatomical landmarks in MR-STAT MRA/MRV and compared MR-STAT MRA/MRV to contrast-enhanced T1-weighted images.

Results: Enhancing arteries and veins in conventional T1-weighted images consistently correlated with, respectively, the PD-based MRA and R2-based MRV from gadolinium-free MR-STAT.

Impact: In addition to fast, high-resolution multiparametric mapping, MR-STAT offers gadolinium-free MRA and MRV without the need of additional scan time, reducing the burden of contrast injections and dispensing with environmentally harmful and expensive gadolinium-based contrast agents.

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