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Abstract #1268

Preliminary Study on Functional MRI-Related Conductivity and Permittivity Changes using Electrical Properties Tomography

Kyu-Jin Jung1, Chuanjiang Cui1, ChanHee Park1, SooHyung Lee1, Siyun Jung1, Dongyeob Han2, and Dong-Hyun Kim1
1Department of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea, Republic of, 2Siemens Healthineers Ltd., Seoul, Korea, Republic of

Synopsis

Keywords: Electromagnetic Tissue Properties, Electromagnetic Tissue Properties

Motivation: While MRI signal intensity is influenced by |B1+|, fMRI-related changes in permittivity, which are related to |B1+| distributions, have not yet been investigated.

Goal(s): Observing fMRI-related changes in conductivity and permittivity, and simulating to verify whether fMRI effects arise solely from electrical properties changes.

Approach: With AFI and bSSFP sequences, |B1+| and φ± are acquired to reconstruct the electrical properties (σ and εr) via electrical properties tomography. Simulations were utilized to validate the B1 field and reconstructed electrical properties.

Results: Activated correlations are observed between brain activation and electrical properties, with simulations demonstrating that changes in electrical properties can mimic fMRI effects.

Impact: Functional MRI-related changes in both electrical conductivity and permittivity are observed during brain activation, potentially enhancing our understanding of the relationships between fMRI effect, vascular factors, and tissue electrical properties.

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Keywords