Keywords: Safety, Pulse Sequence Design
Motivation: OGSE (Oscillating Gradient Spin Echo) is a powerful tool for time-dependent diffusion MRI to detect cell structures at the micron scale. It requires strong gradient to provide b-value at a certain oscillating frequency, which will introduce significant mechanical vibration in the gradient coils.
Goal(s): Our study aims to optimize the trapezoidal oscillating gradient to mitigate the mechanical vibration.
Approach: A convex optimization problem is designed to reduce vibration by minimizing vibration level predicted by the system frequency response function, while ensuring the b-value and OG encoding spectrum through multiple constraints.
Results: Optimized OG waveform can achieve vibration reduction up to 3dB on RMS.
Impact: OG caused mechanical vibration poses significant challenge to MRI hardware, especially in high-performance gradient system. Our vibration optimized OG waveforms can improve subject’s comfort and have potential to enable more precise parameter fitting, enhancing the accuracy of microstructural imaging.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords