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Abstract #1339

Bilateral breast gradient insert prototype for strong diffusion encoding at 3T

Gerrit C. Arends1, Edwin Versteeg1, Feng Jia2, Rokus Valentijn1, Emma D.M. Cooijmans1, Dennis J.W. Klomp1, Maxim Zaitsev2, Chantal M.W. Tax1,3, and Sebastian Littin2
1Center for Image Sciences, University Medical Center Utrecht, Utrecht, Netherlands, 2Department of Radiology, Medical Physics, University of Freiburg, Freiburg, Germany, 3Cardiff University Brain Research Imaging Centre, Cardiff, United Kingdom

Synopsis

Keywords: Gradients, Gradients, Breast cancer, DWI

Motivation: Diffusion MRI can provide endogenous contrast for breast cancer screening. Gradient performance is ultimately limited by physiological constraints, namely PNS.

Goal(s): To develop a high-performance bilateral local breast insert gradient with dedicated bed to enable diffusion encoding for breast cancer screening.

Approach: The gradient coils’ wire path was optimized to achieve maximum local gradient strength, a coil carrier was 3D-printed and wound from Litz-wire. CAD-designed mechanics were fabricated using water-jet cutting.

Results: Field mapping showed gradient efficiency up to 2.20 mT/m/A, enabling a local gradient strength of up to 1.32 T/m when using an amplifier with 600A.

Impact: This setup presents a first step toward a dedicated MRI system for bilateral breast cancer screening using diffusion MRI. It can offer a cost-effective alternative to current screening methods, requiring no contrast agents.

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