Abstract #1365

Robust Nyquist ghost correction for high-resolution EPI using multishot dual-polarity GRAPPA reconstruction

Yuancheng Jiang¹, Yohan Jun^2,3, Qiang Liu⁴, Wen Zhong¹, Yogesh Rathi^3,4, Hua Guo¹, and Berkin Bilgic^2,3

¹Center for Biomedical Imaging Research, School of Biomedical Engineering, Tsinghua University, Beijing, China, ²Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ³Harvard Medical School, Boston, MA, United States, ⁴Department of Psychiatry and Radiology, Brigham and Women's Hospital, Boston, MA, United States

Synopsis

Keywords: Artifacts, Artifacts

Motivation: Multishot EPI acquisition improves image fidelity and reduces distortion but is prone to Nyquist ghosts. Dual-polarity GRAPPA (DPG) effectively addresses ghosts in single-shot EPI but has not been extended to multishot acquisitions.

Goal(s): To develop a robust Nyquist ghost correction method for multishot EPI by tailoring DPG.

Approach: We introduce multishot DPG (msDPG), which uses DPG kernels to synthesize polarity-free data and permits incorporation with advanced regularized reconstruction to further address physiologic shot-to-shot phase variations.

Results: On scanners with ultra-high field (Terra.X) or high-performance gradients (Connectome 2.0), msDPG can effectively reduce ghost levels on multishot EPI data, enabling high-fidelity, submillimeter diffusion imaging.

Impact: The proposed msDPG method provides robust Nyquist ghost correction for multishot EPI, effectively suppressing ghosts on modern scanners and facilitating seamless integration with other advanced reconstruction techniques.

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