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Abstract #1542

Non-contrast MRI based machine learning and radiomics signature can predict the severity of primary lower limb lymphedema

Xingpeng Li1
1radiology, Beijing Shijitan Hospital Affiliated to Capital Medical University, Beijing, China

Synopsis

Keywords: Diagnosis/Prediction, Radiomics

Motivation: At present, there is no application of radiomics in the diagnosis of the severity of primary lower limb lymphedema(PLE).

Goal(s): Develop machine learning models to predict severe PLE.

Approach: 119 patients were divided into non severe group (mild, moderate) and severe group. Used five commonly used machine learning models: Logistic Regression, Support Vector Machine, RandomForest, ExtraTrees, and Light Gradient Boosting Machine.

Results: The ExtraTree model performed the best in the test set, with an AUC of 0.938, sensitivity of 75%, and specificity of 100%. The net benefit of the ExtraTree model was greater than that of the two extreme curves.

Impact: All five models performed well in distinguishing between the nonsevere group and the severe group. NCMRI based machine learning radiomics signature can predict the severity of primary lower limb lymphedema.

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Keywords