Keywords: White Matter, Diagnosis/Prediction
Motivation: Punctate white matter lesions (PWML) are common in the preterm. Since previous studies have primarily concentrated on severe cases, the neurodevelopmental outcomes and its structural connectivity alterations associated with mild lesions require further clarification.
Goal(s): This study aims to investigate the relationship between DTI network parameters and the outcome at a corrected age of 6 months of mild PWML.
Approach: The DTI network characteristics among groups were analyzed.
Results: PWML mainly associated with delayed cognitive development, and decreased local efficiency in left inferior parietal lobule and right supplementary motor area can serve as early diagnostic markers for this adverse outcome.
Impact: This result can offer an early screening plan for identifying preterm infants with mild PWML who are at risk of poor cognitive prognosis, which is beneficial for early intervention and improving outcomes.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords