Keywords: Low-Field MRI, Functional Connectivity, ME GRE EPI, TEDANA, Mid Field
Motivation: Resting state fMRI (rs-fMRI) provides vital neurological information and mid-field scanners offer easier MRI access.
Goal(s): To demonstrate feasibility and reproducibility of rs-fMRI with multi-echo EPI (ME-EPI) acquisition at 0.5 T using a large number of echoes (7) combined with TE-dependent denoising and optimal echo combination.
Approach: We acquire repeated ME-_EPI rs-fMRI acquisitions of eleven healthy volunteers, on 2 consecutive days, at 0.5 T, use ICA to capture networks, and assess reproducibility.
Results: Spatial consistency of correlated regions within a specific network was seen for both individual volunteers and group data. Dice coefficients > 0.5 and ICC ~0.6.
Impact: ME-EPI is feasible for producing reliable rs-fMRI at 0.5 T, potentially expanding access of rs-fMRI in the acute setting.
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