Abstract #1654

Comparison of Lung Ventilation and Perfusion on Commercial 0.55T and 1.5T Systems

Juliet Varghese¹, Katherine Binzel^2,3, Yingmin Liu², Oliver Bieri^4,5, Orlando P. Simonetti^3,6, and Grzegorz Bauman^4,5

¹Department of Biomedical Engineering, The Ohio State University, Columbus, OH, United States, ²Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, United States, ³Department of Radiology, The Ohio State University, Columbus, OH, United States, ⁴Division of Radiological Physics, Department of Radiology, University Hospital Basel, Basel, Switzerland, ⁵Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland, ⁶Division of Cardiovascular Medicine, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States

Synopsis

Keywords: Lung, fMRI (resting state)

Motivation: Non-contrast-enhanced matrix pencil (MP) decomposition pulmonary functional MRI can provide quantitative information about regional ventilation and perfusion impairment in the lung.

Goal(s): To evaluate the impact of field strength and gradient performance on pulmonary functional MP-MRI.

Approach: 2D time-resolved ultra-fast balanced steady state free precession (ufSSFP) datasets were acquired in six healthy volunteers on commercial 0.55T and 1.5T systems. In addition to protocols optimized for each system, parameters matched to the 0.55T gradient performance were also acquired at 1.5T.

Results: The results highlight the benefits of low field for lung imaging despite the gradient performance of the 0.55T system.

Impact: The comparative performance of functional lung MRI using matrix pencil decomposition for estimation of regional fractional ventilation and perfusion on commercial 0.55T and 1.5T systems is demonstrated, highlighting the advantages of low field MRI for pulmonary imaging.

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