Keywords: Quantitative Imaging, Reproductive, Phantom, T1
Motivation: To assess the reliability of quantitative MRI T1 measurements over time and across multiple MRI centers.
Goal(s): To evaluate the consistency of T1 relaxometry across eleven centers over six years using the ISMRM/NIST phantom.
Approach: Inversion-recovery T1 mapping was conducted to assess intra- and inter-site variability, comparing results to reference standards.
Results: T1 values consistently remained within ±5% of reference standards across sites and time, suggesting reliable, stable measurements. This supports the use of quantitative T1 mapping in routine clinical settings and multi-center studies for disease monitoring and treatment assessment.
Impact: This study demonstrates that standardized T1 relaxometry protocols yield consistent and reproducible measurements of the ISMRM/NIST phantom across multiple MRI centers over six years, supporting the clinical applicability of quantitative MRI for multi-center disease monitoring and treatment evaluation.
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