Meeting Banner
Abstract #1689

Fat-water separation in low SNR MRI using Graph Cut and mixed magnitude-complex re-fitting with Tukey's Bi-weighting

Ganeshkumar M1, Devasenathipathy Kandasamy2, Raju Sharma2, Dr Shalimar3, Somil Anshal2, Rajnandini Dasgupta2, and Amit Mehndiratta1,4,5
1Centre for Biomedical Engineering, Indian Institute of Technology - Delhi, New Delhi, India, 2Department of Radio-Diagnosis, All India Institute of Medical Sciences, New Delhi, India, 3Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India, 4Faculty of Medicine and Health, University of New South Wales (UNSW), Sydney, Australia, 5Yardi School of Artificial Intelligence, Indian Institute of Technology - Delhi, New Delhi, India

Synopsis

Keywords: Quantitative Imaging, Quantitative Imaging, Fat-water separation, Fat Quantification, Field Inhomogeneity

Motivation: Optimal fat-water separation in single-shot Multi-Echo MR (ME-MR) on a 3Tesla scanner with large echo-spacing is needed for accurate fat quantification with a reduced Specific Absorption Rate. However, the penalty of increased noise makes this challenging.

Goal(s): This research proposes a novel method for optimal fat-water separation with low SNR single-shot 3T ME-MR with large echo-spacing.

Approach: The proposed method combines the Graph-Cut and Mixed Magnitude-Complex fitting methods, introducing Tukey's bi-weighting during optimization for coping with noise.

Results: Liver Proton-Density-Fat-Fraction% obtained from the proposed method correlated better with the gold standard than the widely used Graph-Cut method in these low SNR ME-MR.

Impact: The Proton-Density-Fat-Fraction maps obtained from fat-water separation with ME-MR could be of diagnostic and prognostic value in many diseases. This study proposes a novel method for handling fat-water separation in noise-prone single-shot ME-MR with large echo-spacing.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords