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Abstract #1743

Assessment of Renal Fibrosis in Patients with Chronic Kidney Disease Using mDIXON-Quant Imaging Technology

Wenhui Wang1, Ye Ju1, liangjie lin2, jiazheng wang2, and Ailian Liu1
1The First Affiliated Hospital, Dalian Medical University, dalian, China, 2Clinical and Technical Support, Philips Healthcare, Beijing, China

Synopsis

Keywords: Kidney, Kidney, mDIXON-Quant Imaging;Chronic Kidney Disease; glomerulosclerosis (GS); R2*; Fat Fraction (FF)

Motivation: Noninvasive prediction of renal fibrosis in patients with chronic kidney disease

Goal(s): mDixon-Quant imaging was used to assess the proportion of glomerulosclerosis in patients with chronic kidney disease

Approach: Two different measurements were used to quantify R2* and fat fraction (FF) generated by the mDIXON-Quant imaging technique, and the difference between low and high GS was analyzed.

Results: Cortical R2* may be useful for early prediction of glomerulosclerosis in patients with CKD

Impact: This study demonstrates that partial parameters obtained by two renal measurements of the mDixon-Quant sequence can noninvasively predict the proportion of glomerulosclerosis in patients with chronic kidney disease.

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