Keywords: Blood Vessels, fMRI (task based), pregnancy, women's health, blood vessels, hypercapnia, modelling
Motivation: Pregnancy induces various physiological changes across the body, including in the brain. Studies have shown structural brain changes in postpartum women, however neurovascular adaptations remain underexplored.
Goal(s): Evaluate neurovascular changes during the postpartum period by measuring cerebrovascular reactivity (CVR) and delay (CVD).
Approach: A group of 23 female participants (13 postpartum women, 10 women with no history of pregnancy) were studied using a 5% CO₂ gas challenge and BOLD fMRI.
Results: Significant differences in CVD were observed in the paracingulate and cingulate gyrus, regions associated with salience, reward, and emotional processing networks. No differences in CVR amplitude were found.
Impact: This is the first MRI study investigating cerebrovascular reactivity changes in the postpartum period. Significant differences in reactivity timing were observed in specific regions of the brain known to be related to salience/reward networks and emotion processing.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords