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Abstract #1823

Early Detection of Asymptomatic LVNC: Diagnostic Utility of Non-Contrast T1 Mapping in Routine Screening

Rui Zhang1, Yanhui Hao1, and Yi Zhu2
1The First Affiliated Hospital of Xi’an Jiaotong University, Xi'an, China, 2Philips Healthcare, China, Beijing, China

Synopsis

Keywords: Quantitative Imaging, Cardiomyopathy

Motivation: Early identification of asymptomatic LVNC is essential for timely intervention to prevent complications.

Goal(s): To evaluate non-contrast T1 mapping’s feasibility for detecting myocardial abnormalities in asymptomatic LVNC patients.

Approach: We retrospectively analyzed 64 patients (45 LVNC, 19 controls) with CMR metrics, including T1 mapping and functional parameters, assessed via ROC and correlation analyses.

Results: T1 values were significantly elevated in LVNC patients (P = 0.002), showing good diagnostic accuracy (AUC = 0.803), while other parameters were non-significant (all P > 0.05).

Impact: Non-contrast T1 mapping effectively detects early myocardial abnormalities in asymptomatic LVNC, allowing precise, routine screening and facilitating early intervention without the need for contrast agents.

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