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Abstract #1862

MR-Eye atlas: a large-scale atlas of the eye based on T1-weighted MR imaging

Jaime Barranco1,2,3,4, Adrian Luyken5, Philipp Stachs6, Oscar Esteban2, Yasser Aleman2, Sönke Langner5,7, Oliver Stachs5,8, Benedetta Franceschiello3,4,9, and Meritxell Bach Cuadra1,2,9
1CIBM Center for Biomedical Imaging, Lausanne, Switzerland, 2Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 3School of Engineering, Institute of Systems Engineering, HES-SO Valais-Wallis, Sion, Switzerland, 4The Sense Innovation and Research Center, Lausanne and Sion, Switzerland, 5Department of Ophthalmology, Rostock University Medical Center, Rostock, Germany, 6Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany, 7Institute for Diagnostic and Interventional Radiology, Pediatric and Neuroradiology, Rostock University Medical Center,, Rostock, Germany, 8Department of Life, Light & Matter, Rostock University Medical Center, Rostock, Germany, 9*These authors provided equal last-authorship contribution, Lausanne, Switzerland

Synopsis

Keywords: Analysis/Processing, Segmentation, Atlas, Eye, MR-Eye

Motivation: Lack of standardized tools for spatial normalization in eye MRI

Goal(s): Develop unbiased eye atlases in MRI

Approach: Through image registration, we create eye reference templates detailing healthy eye structures using T1w MR images

Results: Publicly available large-scale unbiased T1w MR-Eye atlases for males (N=594), females (N=616), and combined (N=1210), along with their detailed labels for healthy eye and orbit structures, also projected onto MNI152 and Colin27 spaces

Impact: The publicly provided large-scale unbiased T1w MR-Eye atlases will facilitate spatial normalization and quantitative analysis in the field of ophthalmic imaging, helping clinicians in the diagnosis of multiple ocular diseases, and enhancing our understanding in sex-specific eye anatomy and physiology.

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Abstract

Keywords