Meeting Banner
Abstract #1911

Numbers of MRI lymph nodes:robust prognosticator bridging radiology and risk quantification of distant metastasis in nasopharyngeal carcinoma

Chao Luo1, Shuqi Li1, Lizhi Liu1, Kan Deng2, Peng Wu3, and Haojiang Li1
1Department of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, China, 2Bayer Healthcare, Radiology, Guangzhou, China, 3Philips Healthcare, Shanghai, China

Synopsis

Keywords: Cancer, Head & Neck/ENT

Motivation: Systematic comprise indicators of MRI-positive lymph nodes (MRI-LNs)

Goal(s): Identify reliable prognostic factors to enhance risk stratification and clinical management of nasopharyngeal carcinoma (NPC)

Approach: In this multicenter retrospective study (N=1,897), thirteen MRI-LNs features concerning number, size, and MRI characteristics were analyzed. Univariate and multivariate analyses identified confounding variables and established predictive model.

Results: Among the 13 MRI-LNs features, only lymph node number (LNN) consistently demonstrated even distribution and independence across cohorts. Adjusting for LNN and necrosis number rendered other features insignificant for DMFS. LNN demonstrated significantly correlated with other MRI-LNs features and mediated their risk of distant metastasis.

Impact: The multicenter validation reinforced the robust prognostic value of LNN in risk discrimination model, N staging optimization, and treatment implication. This study emphasizes LNN's predictive ability in clinical MRI interpretation and risk management.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords