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Abstract #1928

Longitudinal 7T MRI Vessel Wall Imaging in Middle Cerebral Artery Dissection: A 210-Day Case Study

Zhiming Zhen1, Yi-Cheng Hsu2, Ying-Hua Chu2, and Wei Chen1
17T Magnetic Resonance Imaging Translational Medical Center, Department of Radiology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China, 2MR Research Collaboration Team, Siemens Healthineers Ltd, Shanghai, China

Synopsis

Keywords: Blood Vessels, Vessel Wall

Motivation: Middle cerebral artery dissection (MCAD) is a key cause of stroke in young adults, but its long-term progression is poorly understood due to limited follow-up frequency.

Goal(s): This study aims to capture dynamic vessel wall changes in MCAD over 210 days using 7T high-resolution vessel wall imaging.

Approach: We monitored a patient with isolated MCAD across multiple follow-ups, employing HRVWI, TOF-MRA, and SWI.

Results: Key stages observed were symptom improvement with dual antiplatelet therapy, dissection adhesion, recanalization, inflammatory stenosis, and eventual stabilization, offering insights into MCAD’s natural course and markers for prognosis.

Impact: This study demonstrates the potential of 7T HRVWI for capturing long-term vessel wall changes in MCAD, providing critical insights into disease progression and markers for treatment response, which could enhance diagnostic and prognostic strategies in cerebrovascular care.

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